how long should i wait to take nyquil after claritin

How Long Should I Wait to Take Nyquil After Claritin?


If you have been suffering from allergies along with cold or flu symptoms, you may have considered taking both Claritin and Nyquil to find relief. However, it’s essential to understand the proper timing and potential interactions between the two medications to ensure your well-being.


Claritin, known generically as loratadine, is an antihistamine that provides relief from allergic reactions such as sneezing, itching, watery eyes, and runny nose. It is available over-the-counter and in prescription strength. Claritin typically lasts in your system for around 24 hours.


Nyquil, on the other hand, is an over-the-counter medication primarily used to alleviate cold and flu symptoms, including coughing, congestion, headache, sore throat, and minor aches. Nyquil contains several active ingredients, such as acetaminophen, dextromethorphan, and doxylamine succinate, which target specific symptoms. Its effects generally last for about 6-8 hours.

Interactions and Waiting Period

While Claritin and Nyquil have different active ingredients, it’s important to understand their respective effects and potential interactions.

  • Drowsiness: Both Claritin and Nyquil can cause drowsiness as side effects. It is recommended not to combine two medications that cause drowsiness together as it may enhance the effects. If you take them close in time, the combined drowsy effect might make it unsafe to perform activities such as driving or operating machinery. It is advisable to consider non-drowsy alternatives or seek guidance from a healthcare professional.
  • Acetaminophen: Nyquil contains acetaminophen, the same active ingredient found in many pain relievers. Taking additional pain medications that contain acetaminophen while using Nyquil can lead to an increased risk of liver damage. Be cautious and avoid exceeding the recommended daily dosage of acetaminophen.
  • Consult your healthcare professional: To ensure your safety and well-being, it’s always wise to consult with a healthcare professional or pharmacist before combining medications to understand any potential interactions or risks. They can provide personalized advice based on your specific health condition and history.


When it comes to taking Nyquil after Claritin, it is generally recommended to wait at least a few hours between doses to minimize the risk of any potential interactions or intensified side effects. However, it is always best to consult with a healthcare professional for personalized advice based on your unique circumstances.

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